Table 2.
Age-Adjusted Effects of Intensive Lifestyle Intervention and Metformin on Diabetes Progression in Women With or Without a History of Gestational Diabetes Within the DPP/DPPOS
| Placebo |
Metformin |
Lifestyle |
||||
|---|---|---|---|---|---|---|
| GDM | No GDM | GDM | No GDM | GDM | No GDM | |
| Incidence of diabetes (number of cases per 100 person-years)a | 11.4b | 6.9 | 6.8 | 6.7 | 7.6 | 4.9 |
| Reduction in incidence (compared with placebo)a | 40.4c | 3.3 | 35.2c | 29.7c | ||
| Number needed to treat (to prevent one case in 10 y compared with placebo)a | 7.2 | 48.8 | 11.3 | 9.9 | ||
a
Adjusted for age.
b
P < .05 compared with non-GDM group.
c
P < .05 compared with placebo.