Table 1.
DDE-Attributable Childhood Obesity, 2010
| Expert panel evaluation of epidemiological evidence | Moderate | |||||
| Expert panel evaluation of toxicological evidence | Moderate | |||||
| Probability of causation, % | 40–69 | |||||
| Percentile of exposure | 0–9 | 10–24 | 25–49 | 50–74 | 75–89 | >90 |
| Percentile assumed | 0 | 10 | 25 | 50 | 75 | 90 |
| Cord serum DDE, ng/g | <LOD | 10.62 | 22.47 | 50.25 | 112.36 | 211.54 |
| Increment in change in weight for age Z score (main estimate) | 0.00 | 0.00 | 0.004 | 0.01 | 0.03 | 0.06 |
| RR of rapid infant weight gain (sensitivity analysis) | 1.00 | 1.00 | 1.04 | 1.09 | 1.13 | 1.17 |
| Attributable increment in rapid weight gain (main estimate), % | 0.00 | 0.00 | 0.12 | 0.39 | 0.99 | 1.94 |
| Attributable increment in rapid weight gain (sensitivity analysis), % | 0.00 | 0.00 | 1.01 | 2.15 | 3.33 | 4.30 |
| Attributable fraction of overweight at age 10 (main estimate), % | 0.26 | |||||
| Attributable fraction of overweight at age 10 (sensitivity analysis), % | 0.92 | |||||
| Attributable cases of overweight (main estimate) | 1555 | |||||
| Attributable cases of overweight (sensitivity analysis) | 5463 | |||||
| Costs of attributable overweight (main estimate) | €24.6 million | |||||
| Costs of attributable overweight (sensitivity analysis) | €86.4 million |
Abbreviation: LOD, limits of detection.