Figure 6. A, Darkfield emulsion autoradiography images demonstrate the effect of LPS on MCT8 mRNA in brain blood vessels. Images were taken from the thalamus where labeled vessels (arrows) stand out due to virtually undetectable hybridization signal in neurons. The vascular signal vanishes completely by 9 h after LPS. At 24 h, and especially at 48 h, more intense hybridization signal labels a higher number of vessels than in control mice. Scale bar = 200 μm. B, A similar phenomenon is illustrated in images taken from the rat hippocampus. At 9 h after LPS only occasional vessels with faint hybridization signal were detected, whereas several vessels with intense signal were observed at 48 h. Scale bar = 100 μm.