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. 2015 Feb 3;156(4):1303–1315. doi: 10.1210/en.2014-1849

Figure 5. TLR4 blockade abrogated LPS-evoked inhibitory responses in mice ARC neurons.

Figure 5.

A, Summary of the incidence of mice ARC neuronal responses to LPS (10 μg/mL) in slices preincubated in the presence of a purified monoclonal antibody against mouse (mTLR4 antibody, 0.1 μg/mL). B, Bar graphs summarizing the effects LPS on mean firing activity. C, Mean changes in membrane potential in the presence of the mTLR4 antibody (n = number of neurons). Data are represented as mean ± SEM. +, P < .05 (paired t test within its own group); *, P < .05 compared with mTLT4 (no LPS) group (paired t test).