Table 3.
Immunohistochemical findings of gangliocytic paraganglioma
| Epithelioid cells | Spindle-shaped cells | Ganglion-like cells | |
|---|---|---|---|
| bcl-2 | 3/12 (25.0%) | 8/12 (66.7%) | 4/12 (33.3%) |
| CD56 | 12/12 (100%) | 5/12 (41. 7%) | 12/12 (100%) |
| Chromogranin A | 11/12 (91.7%) | 0/0 (0%) | 9/12 (75.0%) |
| Estrogen receptor | 3/12 (25.0%) | 0/0 (0%) | 0/0 (0%) |
| Pancreatic polypeptide | 11/12 (91.7%) | 0/0 (0%) | 11/12 (91.7%) |
| Pan-cytokeratins | 4/12 (33.3%) | 0/0 (0%) | 0/0 (0%) |
| Progesterone receptor | 11/12 (91.7%) | 0/0 (0%) | 0/0 (0%) |
| p53 | 0/0 (0%) | 0/0 (0%) | 0/0 (0%) |
| Somatostatin | 11/12 (91.7%) | 0/0 (0%) | 11/12 (91.7%) |
| Synaptophysin | 12/12 (100%) | 3/12 (25.0%) | 12/12 (100%) |
| S-100 | 1/12 (8.3%) | 12/12 (100%) | 11/12 (91.7%) |
Legend: Results of immunohistochemical examination of the three characteristic tumor components of the collected 12 cases of gangliocytic paraganglioma are summarized.