Table 7.

Immunohistochemical findings of hormone receptors and pancreatic polypeptide

	Estrogen receptor	Progesterone receptor	Pancreatic polypeptide
Immunoreactivity in the epithelioid cells of GP	3 / 12 (25.0%)	11 / 12 (91.7%)	11 / 12 (91.7%)
Immunoreactivity in the NET G1	0 / 6 (0%)	0 / 6 (0%)	0 / 6 (0%)
P value (Chi-Square test)	P = 0.180	P < 0.001	P < 0.001

GP: Gangliocytic paraganglioma, NET: neuroendocrine tumor.

Legend: Duodenal neuroendocrine tumor (NET) G1 except for gangliocytic paraganglioma (GP) showed completely negative reactivity for hormone (estrogen and progesterone) receptors and pancreatic polypeptide. Statistically, GP showed significantly higher positive reactivity for progesterone receptor and pancreatic polypeptide (Chi-square test: P < 0.05 for each).