Table 2.
Variables | Time | PL | Within group | AL300 | Within group | AL500 | Within group | Between group |
---|---|---|---|---|---|---|---|---|
N = 23 | P-value | N = 23 | P-value | N = 24 | P-value | P-value | ||
FBS (mg/dl) | Before intervention | 110 ± 3.91 | - | 112 ± 2.5 | - | 111 ± 4.1 | - | 0.69 |
Fourth week | 109 ± 4.14 | 0.92 | 109 ± 2.77* | 0.006 | 108 ± 3.9* | 0.001 | 0.009* | |
Eighth week | 110 ± 4.22 | 0.19 | 108 ± 2.78* | 0.001 | 104 ± 4.2* | <0.001 | 0.001* | |
Hb A1C (%) | Before intervention | 6.01 ± 0.16 | - | 6 ± 0.24 | - | 6 ± 0.23 | - | 0.37 |
Eighth week | 6.03 ± 0.14 | 0.059 | 5.8 ± 0.21* | 0.042 | 5.6 ± 0.33* | 0.011 | 0.04* | |
LDL-C (mg/dl) | Before intervention | 149.7 ± 1.08 | - | 148.7 ± 0.94 | - | 151.6 ± 1.04 | - | 0.12 |
Fourth week | 150 ± 1.13 | 0.29 | 147.5 ± 0.52 | 0.24 | 146 ± 1.32 | 0.12 | 0.06 | |
Eighth week | 150.7 ± 1.2 | 0.34 | 145.4 ± 1.31 | 0.37 | 137.5 ± 1.44* | 0.01 | 0.01* | |
CHOL-C (mg/dl) | Before intervention | 242 ± 3.13 | - | 241 ± 6.9 | - | 243 ± 10.4 | - | 0.21 |
Fourth week | 242 ± 3.24 | 0.73 | 238 ± 6.4 | 0.25 | 228 ± 11.6 | 0.053 | 0.04* | |
Eighth week | 243 ± 3.52 | 0.92 | 235 ± 8.1 | 0.13 | 218 ± 11.81* | <0.001 | 0.006* | |
TG (mg/dl) | Before intervention | 173 ± 1.41 | - | 176.4 ± 1.5 | - | 179 ± 2.26 | - | 0.78 |
Fourth week | 173.3 ± 1.41 | 0.54 | 178.2 ± 2 | 0.19 | 174.8 ± 2.35 | 0.045 | 0.1 | |
Eighth week | 173.6 ± 1.41 | 0.82 | 175.4 ± 2.08 | 0.072 | 168.6 ± 2.87* | 0.005 | 0.03* | |
HDL-C (mg/dl) | Before intervention | 31.95 ± 1.29 | - | 30.43 ± 1.50 | - | 31.1 ± 2.05 | - | 0.26 |
Fourth week | 31.82 ± 1.15 | 0.18 | 33.6 ± 3.99 | 0.25 | 33.6 ± 3.99 | 0.11 | 0.01* | |
Eighth week | 31.69 ± 1.45 | 0.09 | 35.3 ± 3.73* | 0.08 | 35.3 ± 3.73* | 0.004 | 0.007* |
The within groups p values are for the comparison between the fourth week or the eighth week with baseline in the same group. * p <0.05: compared with the corresponding time in the placebo group.
All data are expressed as Mean ± SD. PL = placebo group. AL300 = the group that received 300 mg capsule of Aloe vera. AL500 = the group that received 500 mg capsule of Aloe vera.