Table 1.
Characteristics of glaucoma patients taking eye drops and control subjects without drops
| Glaucoma group with eye drops (n=79) | Control group without eye drops (n=30) | P-value | P-value adjusted for age | |
|---|---|---|---|---|
| Mean age ± SD (years) | 70.0± 11.7 | 62.4±11.9 | 0.003a | |
| Female-to-male ratio | 45:34 | 17:13 | 0.98b | |
| Antiglaucoma medications | ||||
| Median number of drops (quartile range), n | 2 (1–3) | – | – | |
| Median duration (quartile range), months | 60 (36–120) | – | – | |
| Median of OSDI (quartile range), score | 11.1 (5.0–22.5) | 9.2 (4.8–17.5) | 0.41 | 0.18 |
| Median of Schirmer test (quartile range), mm | 10.0 (5.0–24.0) | 10.0 (5.0–7.8) | 0.93 | 0.19 |
| Median of TBUT (quartile range), seconds | 6.0 (5.0–8.0) | 9.5 (6.0–12.3) | <0.001 | 0.03 |
| Median of fluorescein staining (quartile range), grade | 1.0 (0.75–1.25) | 0 (0–0.25) | <0.001 | <0.001 |
| Median of impression cytology (range), grade | 1.0 (1:2 to 1:6) | 0.6 (1:2 to 1:4) | <0.001 | <0.001 |
Notes: Mann-Whitney U-test; analysis of covariance for age adjustment;
a
Student’s t-test for independent samples;
b
chi-square test; result significant at P<0.05.
Abbreviations: OSDI, ocular surface disease index; SD, standard deviation; TBUT, tear film breakup time.