Table 1.
Baseline Subject Characteristics Stratified by Gender
| Men (n=298) | Women (n=354) | p-value | |
|---|---|---|---|
| Age (years) | 37 ± 9 | 36 ± 9 | 0.07 |
| Diabetes duration (years) | 24 ± 9 | 23 ± 9 | 0.29 |
| HbA1c (%) | 8.0 ± 1.2 | 8.0 ± 1.3 | 0.90 |
| HbA1c (mmol/mol) | 64.0 ± 10.8 | 64.0 ± 11.9 | 0.90 |
| LDL-C (mg/dl) | 104 ± 30 | 98 ± 28 | 0.007 |
| HDL-C(mg/dl) | 51 ± 14 | 60 ± 17 | <0.0001 |
| Triglycerides (mg/dl) | 80 (61–113) | 77 (61–104) | 0.23 |
| SBP (mm Hg) | 121 ± 14 | 114 ± 14 | <0.0001 |
| DBP (mm Hg) | 80 ± 9 | 75 ± 8 | <0.0001 |
| BMI (kg/m2) | 26.5 ± 3.9 | 26.0 ± 4.7 | 0.09 |
| Waist circumference (cm) | 90.3 ± 11.7 | 80.8 ± 12.0 | <0.0001 |
| SUA (mg/dl) | 5.6 ± 1.0 | 4.6 ± 1.0 | <0.0001 |
| AER (μg/min) | 7.4 (4.5–23.8) | 5.8 (3.8–11.8) | <0.0001 |
| ACR (mg/dL) | 6.3 (3.7–21.3) | 6.2 (4.2–12.5) | 0.86 |
| eGFRCYSTATIN C | 107 ± 23 | 106 ± 20 | 0.68 |
| Insulin therapy | 100% | 100% | N/A |
| Metformin | 2.4% | 3.3% | 0.43 |
| Pioglitazone | 0% | 0.6% | 0.19 |
| On antihypertensive medications (%) | 41% | 35% | 0.09 |
| Ever smoker (% yes) | 18% | 22% | 0.21 |
| Any CAC (% yes) | 49 | 28 | <0.0001 |
| Albuminuria (% yes) | 27 | 17 | 0.005 |
| Microalbuminuria (% yes) | 15 | 12 | 0.19 |
| Macroalbuminuria (% yes) | 11 | 6 | 0.01 |
| PDR (% yes) | 27 | 19 | 0.02 |
| Retinopathy (% yes) | 33 | 26 | 0.07 |
Data are means ± SD, % or median (25th – 75th %)