Table 2.
Predictors of Vascular Complications in Stepwise Logistic Regression Analysis
| Incident albuminuria (n=330) | Rapid GFR decline (n=236) | Incident DR (n=361) | Incident PDR (n=392) | CACp (n=455) | |
|---|---|---|---|---|---|
| Variable | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) |
| Age (per 10 years) | – |
2.0 (1.3–3.0) P=0.001 |
0.7 (0.5–1.0) P=0.04 |
– |
1.8 (1.3–2.6) P=0.0004 |
| Diabetes duration (per 10 years) | – | – |
2.4 (1.6–3.8) P<0.0001 |
1.8 (1.1–2.8) P=0.01 |
2.2 (1.5–3.0) P<0.0001 |
| Male sex | – |
0.3 (0.1–0.9) p=0.03 |
– | – | – |
| HbA1c (per 1%) |
1.5 (1.2–2.1) P=0.003 |
– |
1.5 (1.2–1.8) P=0.0004 |
1.8 (1.4–2.3) P<0.0001 |
1.3 (1.1–1.6) P=0.005 |
| SBP (per 10 mmHg) | – | – | – | – |
1.4 (1.2–1.7) P=0.0006 |
| DBP (per 10 mmHg) | – | – |
1.6 (1.1–2.2) P=0.009 |
– | – |
| Anti-hypertensive medications | – |
3.5 (1.4–9.0) P=0.01 |
– | – |
2.1 (1.3–3.4) P=0.003 |
| HDL-C (per 10 mg/dl) | – | – | – | – |
0.8 (0.6–0.9) P=0.0005 |
| SUA (per 1 mg/dl) |
1.8 (1.2–2.7) P=0.004 |
1.9 (1.1–3.3) p=0.03 |
1.4 (1.1–1.9) P=0.01 |
2.1 (1.4–3.0) P=0.0001 |
1.5 (1.1–1.9) P=0.004 |
The odds ratio represents the odds of developing the vascular event per 1-unit increase in the independent variable, unless otherwise specified. Dashes indicate that variable did not enter the model. A separate model was constructed for each outcome.