. Author manuscript; available in PMC: 2015 Oct 1.

Published in final edited form as: Acta Diabetol. 2014 Jun 15;51(5):783–791. doi: 10.1007/s00592-014-0611-1

Table 4.

Prediction Performance Analyses for Models with SUA, SBP, DBP, HbA1c and LDL-C as Continuous Variables

Model 1 (HbA1c, SBP, DBP and LDL-C) vs. model 2 (model 1 + SUA)
*CAC progression (n=199)* Low risk category: <20% Intermediate risk category: 20–50% High risk category: >50%
*Categorical NRI*	*0.12 (95% CI 0.03–0.21)*
■ Percentage of events correctly reclassified	6% (p=0.13)
■ Percentage of non-events correctly reclassified	6% (p=0.04)
*Category free NRI*	*0.44 (95% CI 0.25–0.62)*
■ Percentage of events correctly reclassified	19% (p=0.008)
■ Percentage of non-events correctly reclassified	25% (p<0.0001)
*Incident albuminuria (n=27)* Low risk category: <3% Intermediate risk category: 3–6% High risk category: >6%
*Categorical NRI*	*0.30 (95% CI 0.14–0.46)*
■ Percentage of events correctly reclassified	7% (p=0.32)
■ Percentage of non-events correctly reclassified	23%(p<0.0001)
*Category free NRI*	*0.35 (95% CI −0.04–0.74)*
■ Percentage of events correctly reclassified	11% (p=0.56)
■ Percentage of non-events correctly reclassified	23% (p<0.0001)
*Rapid GFR decline (n=50)*
*Category free NRI*	*0.28 (95% CI −0.01–0.57)*
■ Percentage of events correctly reclassified	12% (p=0.40)
■ Percentage of non-events correctly reclassified	40% (p<0.0001)
*Incident diabetic retinopathy (n=71)*
*Category free NRI*	*0.19 (95% CI −0.07–0.45)*
■ Percentage of events correctly reclassified	4% (p=0.72)
■ Percentage of non-events correctly reclassified	15% (p=0.01)
*Incident peripheral diabetic retinopathy (n=35)*
*Category free NRI*	*0.44 (95% CI 0.10–0.78)*
■ Percentage of events correctly reclassified	14% (p=0.40)
■ Percentage of non-events correctly reclassified	30% (p<0.0001)