Table 2. Incidence and hazard ratio for the osteonecrosis cohort compared to the comparison cohort.
Osteoporosis | Comparison | HR (95% CI) | ||||
---|---|---|---|---|---|---|
Case no. | IR † | Case no. | IR | Crude | Adjusted a | |
Overall | 121 | 11.72 | 110 | 5.32 | 2.20 (1.70–2.85)** | 2.05 (1.58–2.65)** |
Age, year | ||||||
20–64 | 40 | 7.30 | 56 | 5.12 | 1.43 (0.95–2.14) | 1.32 (0.88–2.00) |
≥ 65 | 81 | 16.72 | 54 | 5.53 | 3.02 (2.14–4.26)** | 2.95 (2.09–4.17)** |
Gender | ||||||
Women | 98 | 11.13 | 96 | 5.47 | 2.03 (1.54–270)** | 1.89 (1.42–2.51)** |
Men | 23 | 15.15 | 14 | 4.44 | 3.42 (1.76–6.64)** | 3.19 (1.63–6.24)** |
Comorbidity | ||||||
No | 29 | 7.47 | 45 | 4.41 | 1.70 (1.06–2.71)* | 1.62 (1.01–2.58)* |
Yes | 92 | 14.29 | 65 | 6.19 | 2.31 (1.68–3.17)** | 2.28 (1.66–3.14)** |
Diabetes | ||||||
No | 84 | 10.26 | 80 | 4.64 | 2.21 (1.63–3.00)*** | 2.09 (1.53–2.84)*** |
Yes | 37 | 17.36 | 30 | 8.73 | 1.99 (1.23–3.22)** | 1.95 (1.20–3.16)** |
Hypertension | ||||||
No | 40 | 8.78 | 53 | 4.69 | 1.88 (1.25–2.83)** | 1.74 (1.15–2.63)** |
Yes | 81 | 14.05 | 57 | 6.07 | 2.31 (1.65–3.25)*** | 2.28 (1.62–3.20)*** |
Cancer | ||||||
No | 111 | 11.22 | 107 | 5.33 | 2.10 (1.61–2.74)*** | 1.95 (1.50–2.55)*** |
Yes | 10 | 23.51 | 3 | 4.90 | 4.78 (1.32–17.4)* | 4.90 (1.35–17.8)* |
CI, confidence interval.
aAdjusted model, adjusted for age, gender, hypertension, diabetes, and cancer.
†IR, incidence ratio, per 10,000 person-years.
*P<0.05;
**P<0.01.