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. 2015 Apr 16;10(4):e0124737. doi: 10.1371/journal.pone.0124737

Table 4. Characteristics of male and female offspring of fathers and mothers that received standard chow (SC) and/or high-fat (HF) diet.

Male SC-Mo/SC-Fa SC-Mo/HF-Fa HF-Mo/SC-Fa HF-Mo/HF-Fa
Initial body mass (g) 1.20±0.04a 1.23±0.08a 1.26±0.05a 1.50±0.05 b
Body mass at weaning (g) 9.80±0.85a 9.90±0.58a 11.50±0.67b 12.68±0.77c
Final body mass (g) 25.03±0.35a 25.53±0.97a 28.60±1.10b 31.72±0.88c
Food intake (g/day/mouse) 2.20±0.32a 2.36±0.38a 3.49±0.43b 4.40±0.34c
Energy intake (kJ/day/mouse) 36.32±5.30a 38.97±6.36a 57.62±4.82b 72.65±5.53c
Fasting glucose (mmol/L) 4.55±0.52a 6.69±0.35b 8.12±0.48b 10.21±1.07c
Adiposity Index (%) 2.42±0.27a 2.40±0.27a 3.86±0.53b 5.39±0.45c
Total cholesterol (mg/dL) 67.67±3.14a 70.45±13.10a 90.20±2.65b 112.90±6.36c
Triacylglycerol (mg/dL) 54.75±1.08a 57.00±7.50a 65.77±4.39b 79.90±6.05c
Insulin (pg/mL) 88.60±3.75a 140.20±9.29b 243.50±33.27c 377.80±7.62d
Adiponectin (106 pg/mL) 7.40±0.43a 6.04±0.50b 4.65±0.88c 3.22±0.29d
Hepatic mass (g/cm) 0.34±0.04a 0.53±0.04b 0.50±0.06b 0.70±0.05c
Liver TG (mg/dl/mg) 2.79±0.46a 4.71±0.89b 4.90±0.77b 6.60±0.34c
Female
Initial body mass (g) 1.13±0.03e 1.14±0.04e 1.20±0.10e 1.36±0.05f, *
Body mass at weaning (g) 8.96±0.85e,* 8.99±0.58e,* 10.01±0.67f,* 11.90±0.78g,*
Final body mass (g) 19.13±0.39e,* 19.18±0.63e,* 21.37±0.83f,* 23.47±0.74g,*
Food intake (g/day/mouse) 1.98±0.50e 1.98±0.42e 2.76±0.38f,* 3.52±0.77g,*
Energy intake (kJ/day/mouse) 32.69±8.20e 32.69±6.94e 45.57±6.26f,* 58.12±12.76g,*
Fasting glucose (mmol/L) 3.97±0.35e 5.72±0.26f 6.04±1.04f,* 7.78±0.81g,*
Adiposity Index (%) 3.14±0.06e 3.00±0.17e 4.85±0.20f,* 6.93±0.30g,*
Total cholesterol (mg/dL) 58.17±2.48e 60.13±6.46e 76.83±4.75f, * 95.62±8.43g,*
Triacylglycerol (mg/dL) 53.60±2.67e 55.46±1.43e 60.65±1.90e,* 71.13±2.55f,*
Insulin (pg/mL) 85.98±6.27e 136.60±36.49f 198.40±21.82g,* 279.80±10.90h,*
Adiponectin (106 pg/mL) 8.30±0.51e 7.02±0.48f 5.66±0.90g,* 4.29±0.43h,*
Hepatic mass (g/cm) 0.32±0.04e 0.48±0.05f 0.42±0.07f 0.61±0.07g
Liver TG (mg/dl/mg) 2.64±0.13e 4.33±0.76f 4.46±0.80f 6.25±1.14g

All offspring groups received postnatal SC diet (n = 5). Data are expressed as the mean and SD (n = 5 mice per group, one way ANOVA and the post hoc test of Holm-Sidak). Same letters represent equal groups, with no statistical difference while different letters represent different groups from each other, with statistical difference (P<0.05)

* different from the corresponding counterpart (P<0.05).

Abbreviations: offspring of SC mother and SC father (SC-Mo/SC-Fa); offspring of SC mother and HF father (SC-Mo/HF-Fa); offspring of HF mother and SC father (HF-Mo/SC-Fa); offspring of HF mother and HF father (HF-Mo/HF-Fa); triacylglycerol (TG).