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. 2015 Apr 16;10(4):e0122985. doi: 10.1371/journal.pone.0122985

Table 4. Cut-Off Points, Sensitivity and Specificity for BMI, WC and WHtR Predictive of Cardiovascular Disease Risk Factors.

a. Optimal Cut-Off Points for BMI, WC and WHtR Predictive of CVD Risk Factors
Body Mass Index (BMI) Waist Circumference (WC) Waist-Height Ratio (WHtR)
Cut-off (kg/m2) Sensitivity (%) Specificity (%) Cut-off (cm) Sensitivity (%) Specificity (%) Cut-off Sensitivity (%) Specificity (%)
Male (n = 415)
Diabetes mellitus 23.9 69.0 56.5 88.5 69.0 69.2 0.491 96.6 49.7
Hypertension 23.8 66.7 60.5 84.5 72.1 56.9 0.501 67.6 61.8
High Total Cholesterol 23.5 67.3 58.1 86.5 60.7 65.6 0.479 83.2 46.1
High Triglyceride 23.7 82.4 55.9 88.5 70.6 69.8 0.492 82.4 51.4
Low HDL-Cholesterol 23.5 83.7 53.8 88.5 67.4 70.4 0.491 90.7 50.8
High LDL-Cholesterol 23.5 67.6 58.1 86.5 60.0 65.2 0.479 83.8 46.1
Female (n = 1476)
Diabetes mellitus 27.1 49.2 85.5 82.5 72.3 76.8 0.513 80.0 72.3
Hypertension 27.7 41.1 42.5 83.5 61.6 81.5 0.531 61.0 81.6
High Total Cholesterol 23.6 53.2 67.0 79.5 53.2 70.4 0.460 75.9 48.5
High Triglyceride 25.6 76.3 78.4 83.5 76.3 78.7 0.523 81.6 75.7
Low HDL-Cholesterol 26.1 75.9 80.1 78.8 79.3 63.3 0.497 79.3 62.8
High LDL-Cholesterol 23.5 57.6 66.5 79.5 60.0 70.9 0.499 61.6 68.7
b. Sensitivity and Specificity for BMI, WC and WHtR Predictive of CVD Risk Factors Based On Established/Proposed Cut-Off Points*
Body Mass Index (BMI) Waist Circumference (WC) Waist-Height Ratio (WHtR)
Cut-off (kg/m 2 ) Sensitivity (%) Specificity (%) Cut-off (cm) Sensitivity (%) Specificity (%) Cut-off Sensitivity (%) Specificity (%)
Male (n = 415)
Diabetes mellitus 27.5 24.1 82.1 90 62.1 72.8 0.501 79.3 56.5
Hypertension 27.5 31.5 86.5 90 44.1 75.7 0.501 67.6 61.8
High Total Cholesterol 27.5 26.2 84.4 90 42.1 74.7 0.501 63.6 60.1
High Triglyceride 27.5 41.2 83.7 90 61.8 73.2 0.501 76.5 56.7
Low HDL-Cholesterol 27.5 44.2 84.7 90 95.3 33.6 0.501 76.7 57.5
High LDL-Cholesterol 27.5 25.7 84.2 90 85.7 36.1 0.501 64.8 60.3
Female (n = 1476)
Diabetes mellitus 27.5 43.1 87.6 80 80.0 67.8 0.499 84.6 65.8
Hypertension 27.5 44.5 89.6 80 69.2 69.5 0.499 72.6 67.5
High Total Cholesterol 27.5 22.7 88.5 80 53.2 70.4 0.499 55.6 68.3
High Triglyceride 27.5 42.1 87.0 80 84.2 67.0 0.499 84.2 64.8
Low HDL-Cholesterol 27.5 34.5 86.7 80 75.9 33.5 0.499 72.4 64.3
High LDL-Cholesterol 27.5 25.2 88.6 80 60.0 70.9 0.499 61.6 68.7

*BMI ≥27.5 kg/m2 (High Risk Category, Obesity equivalent for Asians)

WC ≥80cm for females, WC ≥90cm for males (Asian Cut-Offs); WHtR ≥0.5 (Proposed Cut Off)

HDL, high-density lipoprotein; LDL, low-density lipoprotein.