Table 5.
Interaction of pre-pregnancy overweight/obesity status with maternal serum 25[OH]D3 concentrations on gestational diabetes mellitus (GDM)
| GDM | Stratified model | Joint model | ||||
|---|---|---|---|---|---|---|
| Characteristics | Yes (N=135) |
No ( N=517) |
Adjusted OR |
95% (CI) | Adjusted OR | 95% (CI) |
| 25[OH]D3/Body mass index (BMI) | ||||||
| 25[OH] D3≥30 ng/ml, BMI<25kg/m2 | 23 (17.0) | 144 (27.9) | Referent | Referent | Referent | Referent |
| 25[OH] D3<30 ng/ml, BMI<25kg/m2 | 53 (39.3) | 253 (48.9) | 1.29 | (0.75-2.23) | 1.29 | (0.75-2.23) |
| 25[OH] D3≥30 ng/ml, BMI≥25kg/m2 | 10 (7.4) | 34 (6.6) | Referent | Referent | 1.76 | (0.75-4.17) |
| 25[OH] D3<30 ng/ml, BMI≥25kg/m2 | 49 (36.3) | 82 (16.6) | 2.02 | (0.85-4.76) | 3.24 | (1.80-5.83) |
| P-value for interaction | 0.487 | |||||
Vitamin D sufficient, ≥ 30 ng/ml; pre-pregnancy overweight/obese, ≥25kg/m2
Adjusted for season of blood draw, maternal age, race/ethnicity, family history of diabetes
*
Numbers may not add up to total number of GDM cases or non-GDM controls members due to missing