FIGURE 8.

EtOH does not interfere with OPN-receptor interactions or OPN receptor cell surface density. A, integrin CD44 and αvβ3 receptor density on MSC in the absence or presence of EtOH. A fluorescently tagged antibody binding to OPN receptors CD44 and αvβ3 was unaffected by OPN and EtOH exposure, indicating a constant receptor population among treatment groups. B, fluorescent signal of FITC-labeled OPN in the absence and presence of EtOH in MSC. OPN receptor interactions in the presence of EtOH were analyzed using OPN conjugated to FITC. EtOH did not alter OPN-receptor interactions. Data are presented as mean ± S.E. of three experiments.