Table II.
Proteomic analysis of fungal peptides present in brain samples from ALS patients.
| Patients | Total peptides fungi identified with PD 1.3 | Peptides fungi not present in human database | Peptides fungi confirmed with peaks PTM and manual inspection | Certain fungal peptides |
|---|---|---|---|---|
| Patient 6 | ||||
| Fraction A | 159 | 27 | 0 | |
| Fraction B | 188 | 50 | 2 | AVLDLEPGTMDNVR β-tubulin AVCMLSNTTAIAEAWSR. α-tubulin |
| Fraction C | 192 | 37 | 0 | |
| Fraction D | 103 | 15 | 0 | |
| Patient 7 | ||||
| Fraction A | 212 | 48 | 0 | |
| Fraction B | 210 | 49 | 1 | AVCMLSNTTAIAEAWSR. α-tubulin |
| Fraction C | 213 | 33 | 0 | |
| Fraction D | 170 | 27 | 0 | |
| Patient 8 | ||||
| Fraction A | 266 | 68 | 0 | |
| Fraction B | 207 | 48 | 1 | CVSMLSNTTAIAEAWSR. α-tubulin |
| Fraction C | 210 | 34 | 0 | |
| Fraction D | 187 | 31 | 0 |
PD1.3: Proteome Discoverer 1.3 software