Representative immunohistochemical staining of fibulin-1 expression in normal colorectal mucosa and primary colorectal cancer. Weak fibulin-1 expression in normal colorectal mucosa (A). Typical examples of fibulin-1 staining in primary tumor samples: weak staining (B); intense staining (C). (Original magnification, A1, B1, C1: ×100; A2, B2, C2: ×200).