TABLE 1.

Characteristics of 75 study patients with aseptic failure and implant-associated infection

Characteristic	Value		P valueb
	Aseptic failure (n = 36 patients)	Orthopedic implant-associated infection (n = 39 patients)
Median patient age, yrs (range)	73 (27–89)	73 (48–87)	0.968
No. (%) of males	12 (33)	15 (43)	0.554
No. (%) of patients by type of prosthesis
Joint prosthesis (n = 45)	27 (75)	18 (46)	0.091
Fracture fixation device (n = 30)	9 (25)	21 (54)	0.004
No. (%) of patients with clinical signs of infection
Sinus tract	0	8 (21)	<0.001
Other local signs of infectiona	0	19 (49)	<0.001
Visible pus surrounding the implant	0	28 (72)	<0.001
No. (%) of patients with acute inflammation in tissue histopathology	0	32 (82)	<0.001
Mean synovial fluid cell count (range)
Leukocyte count (109/liter)	0.4 (0.05–0.5)	52 (1.2–78)	<0.001
% granulocytes	17 (2–40)	95 (55–98)	<0.001
No. (%) of patients who received antibiotics prior to sampling	0	22 (56)	<0.001

^aLocal signs of infection include warmth, redness, and wound drainage.

^bBolding represents statistical significance.