TABLE 2.

Summary of microarray data analyses applied and the number of genes with altered expression when focused on growth condition^a

Parameter	No. of altered genes	No. of upregulated genes	No. of down-regulated genes
Growth condition sputum
Isolates obtained from blood culture
A3 and B8 isolates together	30	22	8
A3 only	61	37	24
B8 only	163	93	70
Isolates obtained from sputum culture
A2 and B7 isolates together	208	89	119
A2 only	262	141	121
B7 only	359	153	206
Isolates obtained from both blood and sputum
A3, B8, A2, and B7	157	70	87
Growth condition serum
Isolates obtained from blood culture
A3 and B8 isolates together	169	90	79
A3 only	67	33	34
B8 only	304	137	167
Isolates obtained from sputum culture
A2 and B7 isolates together	374	177	197
A2 only	488	200	288
B7 only	381	186	195
Isolates obtained from both blood and sputum
A3, B8, A2, and B7	265	134	131

^aGene changes observed while the same isolate was incubated in sputum or serum compared with the control medium.