TABLE 1.
Comparison of patient characteristics between HAHO-MRSA, HACO-MRSA, and CA-MRSA infections
| Parameter | Value for patients infected with: |
P value (HAHO vs HACO) | Value for patients infected with CA-MRSA | P value (between HAHO-, HACO-, and CA-MRSA) | |
|---|---|---|---|---|---|
| HAHO-MRSA | HACO-MRSA | ||||
| Total no. of patients | 106 (38) | 153 (54) | 23 (8) | ||
| Demographics | |||||
| Age | 0.35 | <0.001 | |||
| Mean (yr) | 59.5 | 57.9 | 43.6 | ||
| Median (yr) | 59.5 | 57 | 42 | ||
| Range (yr) | 19–99 | 19–93 | 20–83 | ||
| 18–24 yr old (no. [%]) | 1 (1) | 4 (3) | 0.58 | 1(4) | 0.001 |
| 25–44 yr old (no. [%]) | 11 (10) | 22 (14) | 12 (52) | ||
| 45–64 yr old (no. [%]) | 55 (52) | 73 (48) | 8 (35) | ||
| ≥65 yr old (no. [%]) | 39 (37) | 54 (35) | 2 (9) | ||
| Gender (no. [%] male) | 63 (59) | 89 (58) | 0.84 | 18 (78) | 0.18 |
| Race (no. [%] white) | 83 (78) | 105 (69) | 0.09 | 18 (78) | 0.19 |
| Source (no. [%]) | |||||
| Primary bacteremia | 83 (78) | 113 (74) | 0.41 | 10 (43) | 0.003 |
| Past medical history (no. [%]) | |||||
| Diabetes | 31 (29) | 62 (40) | 0.06 | 5 (22) | 0.07 |
| Chronic lung disease | 22 (21) | 39 (25) | 0.38 | 0 (0) | 0.02 |
| Renal failure | 19 (18) | 62 (41) | <0.001 | 1 (4) | <0.001 |
| Malignancy | 41 (39) | 32 (21) | <0.001 | 2 (9) | <0.001 |
| Healthcare-associated risk factors, past 12 mo (no. [%]) | |||||
| Hospitalization | 64 (60) | 105 (69) | 0.45 | 0 (0) | <0.001 |
| Use of invasive device | 50 (47) | 88 (58) | 0.029 | 0 (0) | <0.001 |
| Surgery | 45 (42) | 43 (28) | 0.017 | 0 (0) | <0.001 |
| Stay in long-term-care facility (LTCF) | 26 (25) | 56 (37) | 0.04 | 0 (0) | 0.001 |
| Previous MRSA infection/colonization | 15 (14) | 36 (24) | 0.06 | 0 (0) | 0.001 |
| Hemodialysis | 11 (10) | 45 (29) | <0.001 | 0 (0) | <0.001 |
| Other | 11 (10) | 13 (8) | 0.61 | 0 (0) | 0.27 |
| Invasive devices in last 7 days (no. [%]) | |||||
| Central venous catheter/Swan Ganz | 70 (66) | 57 (37) | <0.001 | 0 (0) | <0.001 |
| Foley | 44 (42) | 20 (13) | <0.001 | 0 (0) | <0.001 |
| Ventilation | 32 (30) | 16 (10) | <0.001 | 0 (0) | <0.001 |
| Endotracheal tube | 28 (26) | 10 (6.5) | <0.001 | 0 (0) | <0.001 |
| Hemodialysis | 16 (15) | 48 (31) | 0.003 | 0 (0) | 0.001 |
| Parenteral nutrition | 15 (14) | 7 (4.6) | 0.007 | 0 (0) | 0.03 |
| Drainage tubes | 13 (12) | 9 (5.9) | 0.07 | 0 (0) | 0.06 |
| Other | 22 (21) | 25 (16) | 0.36 | 1 (4) | 0.16 |
| Outcomes (no. [%]) | 0.003 | 0.003 | |||
| Cure | 51 (48) | 73 (48) | 15 (65) | ||
| Death | 30 (28) | 25 (16) | 0.021 | 1 (4) | 0.009 |
| Failure | 0 (0) | 6 (4) | 0 (0) | ||
| Indeterminate/null | 20 (19) | 25 (16) | 6 (26) | ||
| Recurrent/relapse | 5 (5) | 24 (16) | 0.006 | 1 (4) | 0.01 |
| Admitting service (no. [%]) | <0.001 | <0.001 | |||
| Intensive care unit | 16 (15) | 25 (16) | 2 (9) | ||
| Medical | 45 (42) | 101 (66) | 16 (70) | ||
| Surgical | 39 (37) | 17 (11) | 4 (17) | ||
| Others | 6 (5.7) | 10 (6.5) | 1 (4) | ||
| Length of stay (days) | <0.001 | <0.001 | |||
| Mean | 33.2 | 14.6 | 19.7 | ||
| Median | 23.5 | 10 | 9 | ||
| Range | 1–147 | 1–75 | 2–124 | ||
| Disposition (no. [%]) | 0.075 | 0.09 | |||
| Home | 27 (25) | 54 (35) | 10 (43) | ||
| Not applicable or not discharged | 30 (28) | 27 (18) | 2 (8.7) | ||
| Transfer to other facility, LTCF, or rehab center | 49 (46) | 72 (47) | 11 (48) | ||