TABLE 2.
Genotypic and Phenotypic Antimicrobial Susceptibility Characteristics of Bordetella pertussis Isolatesa
| Isolate | Pertactin allele | Pertactin sequence variation | NCBI GenBank database closest match | 23S sequence variation | Erythromycin disk diffusion diameter (mm) | MIC (Etest) (μg/mL) |
|---|---|---|---|---|---|---|
| BP010 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 57 | 0.016 |
| BP022 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 59 | 0.023 |
| BP034 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 52 | 0.023 |
| BP296 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 57 | 0.064 |
| BP120 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 57 | 0.023 |
| BP172 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 58 | 0.023 |
| BP179 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 56 | 0.016 |
| BP186 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 60 | 0.023 |
| BP207 | prn1 | Signal sequence deletion | AB670735.1 | Not present | 64 | 0.016 |
| BP191 | prn2 | S481 disruption | KC445197.1 | Not present | 60 | 0.016 |
| BP279 | prn2 | S481 disruption plus nonsynonymous sequence variationb | KC445197.1 | Not present | 58 | 0.064 |
| BP101 | prn2 | Stop codon | KC445199.1 | Not present | 59 | 0.016 |
a
MIC = minimum inhibitory concentration; NCBI = National Center for Biotechnology Information.
b
BP279 has a nonsynonymous sequence variation (C1577G) compared with KC445197.1.