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. Author manuscript; available in PMC: 2015 Apr 17.
Published in final edited form as: Head Neck. 2013 Jun 1;36(3):375–384. doi: 10.1002/hed.23316

Figure 4.

Figure 4

Figure 4

Figure 4

Src inhibitors suppress cell proliferation in TPC-1 cells only. The proliferation assay was done using MTT to determine the number of cells by measuring the absorption at 570 nM each day. Each time point was determined in triplicates and all assays were repeated at least once. (A) TPC-1 cells were treated with 0.1 or 1 μM PP2, 0.1 or 1 μM SU6656, or 0.01 or 0.1 μM dasatinib for indicated days at 37°C. (B) K2 cells were treated with 5 or 10 μM PP2, 5 or 10 μM SU6656, or 0.01 or 0.1 μM dasatinib for indicated days at 37°C. (C) TPC-1 and K2 cells were transfected with si-control or si-Src and plated in 24-well plates in triplicate at day 0 and cell growth was monitored for indicated days at 37°C. CI-1040 (1 μM) was added to TPC-1 cells transfected with si-Src RNA and DMSO was added to TPC-1 cells transfected with si-control or si-Src as controls at day 0 after cells were attached to plates.