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. 2015 Mar 6;4(2):92–99. doi: 10.1530/EC-15-0003

Table 3.

Hormone levels, basal and after administration of 1 μg ACTH and 0.25 mg dexamethasone (dex) – healthy subjects vs T2D, subdivided by gender.

T2D men (n=11) T2D women (n=10) P T2D men vs women Healthy men (n=20) Healthy women (n=18) P healthy men vs women P T2D vs healthy men P T2D vs healthy women
S-IGF1, basal (s.d.) 0.4±0.5 0.2±0.3 NS 0.2±0.2 0.3±0.2 NS NS NS
S-IGFBP1, basal (μg/l) 37±4 34±5 NS 32±4 38±5 NS NS NS
S-cortisol, basal before ACTH (nmol/l) 451±43 391±26 NS 368±22 403±22 NS NS NS
S-cortisol, peak after ACTH (nmol/l) 691±42 696±47 NS 582±21 675±26 0.023 0.024 NS
Δ cortisol after ACTH (nmol/l) 240±31 305±42 NS 214±23 267±17 NS NS NS
S-cortisol, basal before dex (nmol/l) 473±40 423±43 NS 409±22 380±22 NS NS NS
S-cortisol, after dex (nmol/l) 321±42 244±24 NS 280±21 240±22 NS NS NS
Δ cortisol after dex (%) −32.0±7.3 −40.4±5.8 NS −32.2±2.9 −39.7±5.1 NS NS NS