Table 4.

Hormone levels, basal after administration of 1 μg ACTH and 0.25 mg dexamethasone (dex) – subjects with type 2 diabetes (T2D) vs healthy subjects. Mean±s.e.m.

	T2D (n=21)	Healthy (n=39)	P
S-IGF1, basal (s.d.)	0.3±0.3	0.3±0.1	NS
S-IGFBP1, basal (μg/l)	36±3	35±3	NS
S-cortisol, basal before ACTH (mmol/l)	424±27	385±16	NS
S-cortisol, peak level after ACTH (nmol/l)	693±31	624±18	0.043
Δ cortisol from basal to peak level after ACTH (nmol/l)	269±26	239±15	NS
S-cortisol, basal before dexamethasone (nmol/l)	448±29	404±15	NS
S-cortisol, after dexamethasone (nmol/l)	283±25	261±15	NS
Δ cortisol from basal after dexamethasone (%)	−36.2±4.6	−35.6±2.9	NS