2.

Characteristics of control and AD patients (mean ± SD)

Demographic variables	Control subjects	AD subjects
Number of subjects	5	5
Gender (male/female)	3/2	3/2
Age at death (yrs)	87.0 ± 3.94	85.8 ± 6.02
Postmortem interval (hr)	2.9 ± 0.70	3.4 ± 1.4
MMSE; number of months prior to death test taken	28 ± 0.8;6.6 ±1.4	15.7 ± 2.6;19.7 ± 1.0
APOE genotype, if known (N)	3/3 (3) 3/4 (2)	ND

AD, Alzheimer's disease; MMSE, mini-mental state examination;APOE, apolipoprotein E; ND, not determined; N, number of individuals; SD, standard deviation; COPD, chronic obstructive pulmonary disease (adapted from [35]).