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. 2008 May 21;12(3):975–986. doi: 10.1111/j.1582-4934.2008.00161.x

2.

Effect of SFLLRN peptide and thrombin on mRNA and protein levels of t-PA, u-PA, u-PAR, PAI-1 and PAI-2

SFLLRN 75 μM Thrombin 10 nM
mRNA fold-ratio (%± SD) Protein fold-ratio (%± SD) mRNA fold-ratio (%± SD) Protein fold-ratio (%± SD)
u-PA 420 ± 10 214 ± 71 795 ± 95 273 ± 26
secreted: 537 ± 362 secreted: 258 ± 16
u-PAR 400 ± 110 283 ± 70 275 ± 45 331 ± 104
t-PA 230 ± 11 263 ± 36 370 ± 170 442 ± 309
PAI-1 235 ± 55 129 ± 17 220 ± 20 132 ± 26
PAI-2 415 ± 55 Not detectable 150 ± 24 Not detectable