2.
Relationship between serum proliferative activity (% of control serum value) (mean±S.D.) and clinicopathologic variables in patients with colorectal cancer
| Patient number (n) | Proliferation (%) | Significance | |
|---|---|---|---|
| Primary tumour location | |||
| Colon | 29 | 208 ± 47 | |
| Rectum | 24 | 220 ± 34 | P= 0.276* |
| TNM stage | |||
| T1/2N0M0 | 9 | 219 ± 46 | |
| T3/4N0M0 | 26 | 209 ± 43 | |
| T1/2N1M0 | 5 | 209 ± 34 | |
| T3/4N1M0 | 3 | 228 ± 56 | |
| T4NxM0 | 2 | 213 ± 20 | |
| T4NxM1 | 8 | 217 ± 44 | P= 0.971** |
| Histologic grade | |||
| 1 Poorly differentiated | 17 | 223 ± 37 | |
| 2 Moderately differentiated | 28 | 206 ± 47 | |
| 3 Well differentiated | 5 | 211 ± 24 | P= 0.404** |
| Unknown | 3 | ||
| Tumour category | |||
| pT1 | 1 | 252 | |
| pT2 | 9 | 207 ± 49 | |
| pT3 | 33 | 214 ± 36 | |
| pT4 | 10 | 212 ± 54 | P= 0.798** |
| Lymph node metastases | |||
| Absent | 36 | 214 ± 42 | |
| Present | 13 | 214 ± 40 | P= 0.962* |
| Unknown | 4 | ||
| Distant metastases | |||
| Absent | 45 | 212 ± 41 | |
| Present | 8 | 218 ± 44 | P= 0.746* |
*
Student's t-test.
*
*One-way ANOVA.