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1.

Mean characteristics of β1-adrenoceptor binding sites in myocardial membranes homogenates from NE treated and control rats

Bmax Controls 1 hr 4 hrs 8 hrs 24 hrs 48 hrs
Mean 959.67 1194.00 1278.67 1215.00 1089.00 976.00
S.D. 31.660 111.906 178.374 184.724 111.879 30.116
p< 0.025 0.038 0.078 0.126 0.553
Kd Controls 1 hr 4 hrs 8 hrs 24 hrs 48 hrs
Mean 0.97 5.28 2.60 1.55 1.16 1.47
S.D. 0.454 0.116 0.840 1.076 0.799 0.935
p< 0.0001 0.042 0.438 0.743 0.452

Bmax (pmoli/mg membrane protein); Kd (pM); values are the means ± S.D. of three animals. t-test: p < 0.05 was considered significant.