Figure 4.

DIANA miRPath analysis of target genes for miRNAs upregulated in AD blood. The set of 13 miRNAs upregulated in AD, except for hsa-miR-6513–3p whose information is absent in DIANA-microT, was imported into DIANA miRPath. It identified the second-rank significant KEGG pathway potentially downregulated in AD, termed long-term potentiation (hsa04720), relevant to target gene network for imported miRNAs. The genes targeted by more than one miRNA are colored by orange, while the genes targeted by a single miRNA are colored by yellow.