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5.

5

Co-localization of Cav-2 and FAK / c-Kit in Cav-1+/+ and Cav-1−/− mouse LVM. In Cav-1+/+ Cav-2 (green) (closed arrow) appears only at CEC (nucleus: small asterisks) and FAK (red) (open arrow) only at FB (nucleus: large asterisks). An anastomotic structure appears (open arrowhead) (A–C). Cav-2 (green) doesn't co-localize with c-Kit (red). Arrow indicates for FB, large asterisk for FB nucleus and small asterisk for CEC nucleus (E–G). In Cav-1−/− FAK and c-Kit are missing with Cav-1 (D and H). CM is cardiomyocyte and IS is interstitial space. Scale bar is 10 mm for all images.