3.
Co-localization between proteins in Cav-1+/+ mouse left ventricular myocardium
| Proteins | CM | CEC | FB | ICLC | ||||
|---|---|---|---|---|---|---|---|---|
| PM | z-line | MF | ||||||
| MMP-2 + Cav-1 | +++ | + | + | +++ | +++ | n/a | ||
| MMP-2 + Cav-2 | - | - | - | +++ | - | n/a | ||
| MMP-2 + Cav-3 | +++ | +++ | +++ | ++ | + | n/a | ||
| MMP-2 + FAK | - | - | - | - | +++ | n/a | ||
| MMP-2 + DDR2 | - | - | - | - | +++ | - | ||
| MMP-2 + vWF | - | - | - | +++ | - | - | ||
| MMP-2 + c-Kit | - | - | - | - | +/- | +++ | ||
| Cav-1 + Cav-2 | - | - | - | + | - | n/a | ||
| Cav-1 + Cav-3 | ++ | + | + | ++ | + | n/a | ||
| Cav-2 + Cav-3 | - | - | - | ++ | - | n/a | ||
| Cav-1 + FAK | - | - | - | - | +++ | n/a | ||
| Cav-1 + vWF | - | - | - | +++ | - | - | ||
| Cav-1 + DDR2 | - | - | - | - | +++ | - | ||
| Cav-1 + c-Kit | - | - | - | - | +/- | +++ | ||
| Cav-2 + FAK | - | - | - | - | - | n/a | ||
| Cav-2 + c-Kit | - | - | - | - | - | - | ||
| Cav-3 + FAK | - | - | - | - | ++ | n/a | ||
| Cav-3 + DDR2 | - | - | - | - | + | - | ||
| Cav-3 + vWF | - | - | - | - | - | - | ||
| Cav-3 + c-Kit | - | - | - | - | +/- | ++ | ||
| FAK + vWF | - | - | - | - | - | - | ||
| DDR2 + c-Kit | - | - | - | - | +/- | +/- | ||
CM, cardiomyocytes; FB, fibroblasts; CEC, capillary endothelial cells; ICLC, interstitial Cajal-like cells; PM, plasma membranes; MF, myofilaments; MMP-2, matrix metalloprotenase-2; Cav-1, caveolin-1; Cav-2, caveolin-2; Cav-3, caveolin-3; FAK, focal adhesion kinase; DDR2, discoidin domain receptor-2; vWF, von Willebrand factor; c-Kit, receptor tyrosine kinase;+, ++ and +++ indicate immunoreactive intensity; - means absent or inconspicuous; +/- means present occasionally.