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SELDI-TOF-MS analysis. Proteolytic activity of ADAM8 in cell culture super-natants assessed by SELDI-TOF-MS. (A) Trace-view and gel view of the mass spectra between 30 and 50 kD of the control siRNA and ADAM8 siRNA #1 transfected cells. Arrow points to the 39.2 kD protein and its suppression in siRNA transfected cells. (B) Decreased intensities of protein peak (arrows) in control siRNA transfected cells.
