Table S1.
Clinical characteristics of phenotypes between the follow-up group and dropouts at baseline
| Follow-up group (n=193) | Dropouts (n=68) | P-value | |
|---|---|---|---|
| SGRQ total score | 29.7±1.2 | 38.0±2.0 | <0.01 |
| SGRQ symptom score | 42.7±1.6 | 46.0±2.7 | 0.29 |
| SGRQ activity score | 39.8±1.7 | 50.9±2.8 | <0.01 |
| SGRQ impact score | 19.8±1.2 | 28.1±2.0 | <0.01 |
| Age (y) | 68.7±0.6 | 72.0±0.9 | <0.01 |
| BMI (kg/m2) | 22.6±0.2 | 21.3±0.4 | 0.01 |
| Pack-years | 64.5±2.2 | 57.3±3.6 | 0.09 |
| mMRC dyspnea scale | 1.4±0.1 | 1.6±0.1 | 0.09 |
| Post-bronchodilator FEV1 (%) | 64.9±1.6 | 63.9±2.7 | 0.73 |
| DLco (mmol/min/mmHg) | 12.4±4.6 | 10.7±4.9 | <0.01 |
| Kco (mmol/min/mmHg) | 2.9±1.1 | 2.5±1.1 | 0.02 |
| White blood cell count (cells/mm3) | 6,139±107 | 6,039±180 | 0.63 |
| Blood eosinophil count (cells/mm3) | 194±10 | 215±16 | 0.27 |
| CRP (mg/dL) | 0.25±0.04 | 0.46±0.07 | 0.01 |
| Serum total IgE (IU/mL) | 217±42 | 217±70 | 0.99 |
Note: P-values were calculated using Student’s t-test.
Abbreviations: BMI, body mass index; CRP, C reactive protein; DLco, carbon monoxide diffusing capacity; FEV1, forced expiratory volume in 1 second; IgE, immunoglobulin E; Kco, carbon monoxide transfer coefficient; mMRC, modified Medical Research Council; SGRQ, St George’s Respiratory Questionnaire.