Fig 11. Phylogenetic analysis of TIM; relationship between R17, S79 and NG pairs in Eukarya TIMs.

The Eukarya domain was extracted from the complete phylogenetic tree and analyzed. NG pairs present in Eukarya sequences are shown in red; residues occurring at positions 17 and 79 are shown in the right columns. Numbering according to the HsTIM sequence is shown at the top of the figure. Color bars indicate major evolutionary grades with a color code as follows: mammals, blue; sauropsidae (reptiles and birds), cyan; anamniotae (fishes and amphibians), purple; arthropodae, brown; nematodae, yellow; green algae, olive; plants, green; kinetoplastidae, orange; fungi, gray; chromalveolata, red.