Fig. 3.

U937 monocytic cells, using the receptor CD44 (red), bind to hyaluronan cable structures (green) on the surface of poly(I:C)-stimulated cultures of intestinal smooth muscle cells at 4 °C (left panel) [6]. When the cultures are warmed (37 °C for 30 min), the monocytic cells relocate, or ‘cap’, CD44 to one pole and internalize hyaluronan as shown in the enlarged inset. The left panel is reprinted from ref. [6] with permission from the American Society for Investigative Pathology.