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. Author manuscript; available in PMC: 2015 Apr 17.
Published in final edited form as: JAMA Surg. 2014 Dec;149(12):1244–1253. doi: 10.1001/jamasurg.2014.556

Table 3.

Final Proportional Hazards Model for Lung Cancer Specific Survival

Variable HR 95%CI P>X2
Treatment
    Lobectomy (Baseline) 1.00 -- --
    Sublobar Resection 1.50 1.29 – 1.75 <.001
    SABR 1.44 1.03 – 2.02 0.03
Age
    66–69 (Baseline) 1.00 -- --
    70–74 1.29 1.09 – 1.52 <.001
    75–79 1.37 1.16 – 1.62 <.001
    ≥80 1.66 1.40 – 1.98 <.001
Sex
    Male (Baseline) 1.00 -- --
    Female 0.75 0.67 – 0.83 <.001
Educational Attainment
    1st Quartile (0 – 10%) 1.00 -- --
    2nd Quartile (10 – 17%) 1.15 0.99 – 1.33 0.07
    3rd Quartile (17 – 27%) 1.21 1.04 – 1.40 0.01
    4th Quartile (>27%) 1.30 1.11 – 1.51 0.00
COPD
    No (Baseline) 1.00 -- --
    Yes 1.25 1.16 – 1.34 <.001
Charleson Comorbidity Score Ex. COPD
    0 (Baseline) 1.00 -- --
    1 1.03 0.90 – 1.17 0.69
    ≥2 1.30 1.13 – 1.49 <.001
Oxygen Supplementation
    No (Baseline) 1.00 -- --
    Yes 1.35 1.17 – 1.55 <.001
T-Stage
    T1A (0.0 – 2.0 cm) (Baseline) 1.00 -- --
    T1B (2.1 – 3.0 cm) 1.30 1.15 – 1.47 <.001
    T2A (3.1 – 5.0 cm) 1.60 1.40 – 1.83 <.001
Histology
    NSCLC, NOS (Baseline) 1.00 -- --
    Adenocarcinoma 0.82 0.67 – 1.01 0.06
    Squamous carcinoma 0.95 0.77 – 1.17 0.63
    Large cell 0.99 0.72 – 1.35 0.94
Mediastinal Sampling
    Not Performed (Baseline) 1.00 -- --
    Performed 0.78 0.78 – 0.78 <.001
Year of Diagnosis
    2003 (Baseline) 1.00 -- --
    2004 0.92 0.79 – 1.08 0.31
    2005 0.96 0.81 – 1.13 0.59
    2006 0.90 0.75 – 1.08 0.26
    2007 0.76 0.62 – 0.94 0.01
    2008 0.76 0.59 – 0.97 0.03
    2009 0.55 0.36 – 0.84 0.01

Abbreviations: HR, hazard ratio; CI, confidence interval; SABR, stereotactic ablative radiation; Ex, excluding; NSCLC, NOS, non-small cell lung cancer, not otherwise specified