Table 2.
Animal characteristics for EDL (n = 53) and SOL (n = 47) groups. Adult mice (EDL n = 15, SOL n = 12) were used as the reference group to the old (EDL n = 14, SOL n = 12) and elderly (EDL n = 24, SOL = 23). p value was taken from one-way ANOVA (Tukey’s HSD post hoc test)
| Adult (5–7 months) | Old (22–26 months) | Elderly (27–32 months) | p value | |
|---|---|---|---|---|
| EDL | ||||
| Mean age (months) | 6.8 ± 0.1 | 23.0 ± 0.4 | 29.9 ± 0.3 | |
| Body mass (g) | 31.7 ± 0.8 | 37.1 ± 1.6a | 32.7 ± 0.7 | 0.006 |
| Mass (mg) | 15.4 ± 3.2 | 13.4 ± 1.8 | 11.5 ± 2.3a | <0.001 |
| PCSA (mm2) | 1.23 ± 0.29 | 1.02 ± 0.14a | 0.9 ± 0.22a | <0.001 |
| P 0 (mN) | 388 ± 17 | 356 ± 16a | 279 ± 13a, b | <0.001 |
| SOL | ||||
| Mean age (months) | 7.0 ± 0.02 | 23.3 ± 0.5 | 29.9 ± 0.3 | |
| Body mass (g) | 31.1 ± 0.8 | 41.5 ± 3.0a | 32.7 ± 0.7b | <0.001 |
| Mass (mg) | 14.0 ± 1.4 | 12.2 ± 0.4 | 11.9 ± 0.6 | 0.197 |
| PCSA (mm2) | 1.16 ± 0.11 | 1.04 ± 0.04 | 1.03 ± 0.06 | 0.431 |
| P 0 (mN) | 187 ± 10 | 195 ± 13 | 166 ± 7 | 0.059 |
Note: a = different than adult and b = different than old (p < 0.05) (marked only on old and elderly)
PCSA physiological cross-sectional area of muscle, P 0 maximum tetanic contractile force, mN millinewtons