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. Author manuscript; available in PMC: 2015 Oct 16.
Published in final edited form as: Nature. 2015 Jan 26;520(7547):378–382. doi: 10.1038/nature14044

Extended Data Fig. 2. TaPin1 is conserved between Theileria annulata and Theileria parva.

Extended Data Fig. 2

a. As the T.parva TpPin1 sequence did not have an annotated signal peptide, we re-analyzed sequence alignment of pin1 genes in T. annulata (TaPin1) and T. parva (TpPin1) (blast-NCBI). The annotated T. annulata intron is indicated in grey and the annotated Methionine codon (ATG) in T. parva in black (underlined). TaPin1 and TpPin1 are well conserved including in the intronic sequence. We conclude that the T.parva TpPin1 annotation should be modified in light of our PCR and Western blot analysis (see Figures 1b and Extended Data 5c).

a. Sequence alignment of pin1 genes in T. annulata (TaPin1) and T. orientalis (ToPin1) (blast-NCBI). The annotated T. annulata intron is indicated in grey and the annotated Methionine codon in T. orientalis in black (underlined). TaPin1 and ToPin1 are less conserved than TaPin1 and TpPin1.