Table 2. Pathway analysis.
Pathway | Signature | P value |
---|---|---|
TGF-beta signaling pathway | early peak | 2.2e-04* |
Oxidative stress response | early peak | 3.9e-04* |
Platelet derived growth factor (PDGF) signaling pathway | early peak | 5.2e-03 |
Angiotensin II-stimulated signaling through G proteins and beta-arrestin | early peak | 0.024 |
Phosphatidylinositol 3 (PI3)-kinase pathway | early peak | 0.016 |
Angiogenesis | early peak | 0.021 |
Toll receptor signaling pathway | late peak | 8.6e-05* |
Integrin signalling pathway | late peak | 8.5e-04* |
Cadherin signaling pathway | late peak | 8.4e-03 |
Apoptosis signaling pathway | late peak | 0.037 |
Notch signaling pathway | decay | 3.3e-03 |
P values for the over-representation of CAGE clusters in 73 Panther gene sets containing at least 20 genes. P values are calculated by hypergeometric test on the counts of clusters from all four data sets combined. Only pathways with p values ≤ 0.05 are listed (those with a FDR significant at 0.1 are indicated by *).