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. 2015 Apr 17;11(4):e1004217. doi: 10.1371/journal.pcbi.1004217

Table 2. Pathway analysis.

Pathway Signature P value
TGF-beta signaling pathway early peak 2.2e-04*
Oxidative stress response early peak 3.9e-04*
Platelet derived growth factor (PDGF) signaling pathway early peak 5.2e-03
Angiotensin II-stimulated signaling through G proteins and beta-arrestin early peak 0.024
Phosphatidylinositol 3 (PI3)-kinase pathway early peak 0.016
Angiogenesis early peak 0.021
Toll receptor signaling pathway late peak 8.6e-05*
Integrin signalling pathway late peak 8.5e-04*
Cadherin signaling pathway late peak 8.4e-03
Apoptosis signaling pathway late peak 0.037
Notch signaling pathway decay 3.3e-03

P values for the over-representation of CAGE clusters in 73 Panther gene sets containing at least 20 genes. P values are calculated by hypergeometric test on the counts of clusters from all four data sets combined. Only pathways with p values ≤ 0.05 are listed (those with a FDR significant at 0.1 are indicated by *).