Table 2. Model predicted means and their differences.
| Variable | Intervention group mean (s.e.) | Control group mean (s.e.) | difference of means (95%CI) | residual variance (covariance of neighbouring time points) |
|---|---|---|---|---|
| Activities of daily living (ADCS ADL total score) | T0: 60.55 (0.91) | T0: 60.53 (0.91) | T0: 0.02 (-2.57–2.61) | 12.45 |
| T1: 62.35 (0.91) | T1: 57.47 (0.91) | T1: 4.89 (2.30–7.48) | (0.50) | |
| T2: 61.26 (1.00) | T2: 53.50 (0.94) | T2: 7.76 (5.01–10.51) a) | ||
| Neuropsychiatric symptom profiles (NPI total score) | T0: 11.25 (1.26) | T0: 11.77 (1.26) | T0: -0.51 (-4.15–3.10) | 22.91 (0.45) |
| T1: 10.05 (1.26) | T1: 15.71 (1.26) | T1: -5.66 (-9.28 –-2.03) | ||
| T2: 10.40 (1.38) | T2: 16.09 (1.29) | T2: -5.69 (-9.55 –-1.83) a) | ||
| Executive function and language ability (semantic word fluency, number of words) | T0: 13.60 (0.65) | T0: 13.92 (0.65) | T0: -0.32 (-2.17–1.53) | 6.21 |
| T1: 15.27 (0.65) | T1: 12.46 (0.65) | T1: 2.81 (0.96–4.66) | (0.39) | |
| T2: 14.15 (0.69) | T2: 12.05 (0.67) | T2: 2.10 (0.18–4.02) a) | ||
| Reaction time and motor skills (Fetz-test, meter) | T0: 0.27 (0.01) | T0: 0.27 (0.01) | T0: 0.001 (-0.02–0.02) | 0.00077 |
| T1: 0.23 (0.01) | T1: 0.28 (0.01) | T1: -0.052 (-0.08 –-0.03) | (0.1822) | |
| T2: 0.24 (0.01) | T2: 0.27 (0.01) | T2: -0.03 (-0.05 –-0.01) a) | ||
| Caregiver burden (NPI-caregiver total score) | T0: 5.58 (0.96) | T0: 5.82 (0.96) | T0: -0.24 (-2.97–2.49) | 13.50 |
| T1: 5.51 (0.96) | T1: 9.55 (0.96) | T1: -4.04 (-6.77 –-1.31) | (0.39) | |
| T2: 6.71 (1.05) | T2: 9.00 (0.98) | T2: -2.29 (-5.20–0.62) | ||
| MMSE (total score) | T0: 22.05 (0.54) | T0: 21.95 (0.54) | T0: 0.10 (-1.43–1.63) | 4.30 |
| T1: 21.99 (0.54) | T1: 21.28 (0.54) | T1: 0.70 (-0.83–2.23) | (0.35) | |
| T2: 22.11 (0.57) | T2: 20.72 (0.55) | T2: 1.39 (-0.21–2.98) |
a) significant at T2 (p<0.05); T0: baseline, T1: 3 months later or after completion of the intervention, T2: 3 month follow-up.; Results of the FETZ-test are given in meters, the lower the number the shorter the reaction time.