Table 3. Comparison of anesthetic procedures between the two groups during the maintenance phase.
| Closed-loop (n = 89) | Opened-loop (n = 86) | P | ||
|---|---|---|---|---|
| Maintenance time | (min) | 199.3±96.2 | 202.5±101.0 | 0.832 |
| Propofol | ||||
| Mean dose | (mg/kg∙h) | 5.28±1.32 | 5.52±1.29 | 0.230 |
| Mean target concentration | (μg/ml) | 2.32±0.58 | 2.56±0.57 | 0.006 |
| Adjusted times | (/h) | 31.55±9.46 | 6.84±6.21 | 0.000 |
| Remifentanil | ||||
| Mean dose | (μg/kg∙h) | 11.14±3.08 | 11.05±3.30 | 0.848 |
| Mean target concentration | (ng/ml) | 5.01±1.25 | 4.87±1.22 | 0.465 |
| Adjusted times | (/h) | 2.62±2.06 | 3.61±2.68 | 0.007 |
| Rocuronium | ||||
| Mean dose | (mg/kg∙h) | 0.59±0.18 | 0.58±0.18 | 0.770 |
| Time of dose added | (/h) | 2.80±0.90 | 2.84±1.16 | 0.771 |
| Blood loss >500ml | n (%) | 11(12) | 15(17) | 0.345 |
| Average transfusion volume | (ml/kg∙h) | 9.77±3.56 | 10.07±4.15 | 0.606 |
| Blood pressure adjustment | n (%) | 30(33) | 34(40) | 0.440 |
| Tramadol | (mg/kg) | 2.03±1.27 | 2.05±1.08 | 0.889 |
| Time to tracheal extubation | (min) | 8.9±4.0 | 9.2±4.0 | 0.579 |
Data are presented as mean ± SD; or number (%).
Closed-loop = automated control of propofol infusion group guided by the bispectral index; Opened-loop = manual control infusion group guided by the bispectral index.