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. 2015 Apr 17;10(4):e0123586. doi: 10.1371/journal.pone.0123586

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© 2015 Ma et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — A and B showed isotype Ig staining in control renal tissue. Biopsy taken from normal renal tissue showed expression of HMGB1 mainly inside nuclei (C, D). Renal tissue of the active AAV patient showed strong cytoplasmic and extracellular staining for HMGB1 in tubuli and glomeruli (E, F).