Table 2. Comparison of mean computed strains to reported mean experimental strains measured with confocal microscopy on compressed growth plate explants.
| Study level | Applied strain (%) | Strain measure | RZ strain (%) | PZ strain (%) | HZ strain (%) | Epi- and meta-physeal bone left on explant | Thickness of RZ + P/H zones (mm) | RZ thickness (% of physeal height) | Study |
|---|---|---|---|---|---|---|---|---|---|
| tissue | -20 | PC*- surface (50 μm depth) | -14 | -14 | -20 | Yes | 0.67 | 31 | Present computational model |
| PC*-interior | -10 | -22 | -14 | ||||||
| cell | -20 | Surface (300 μm depth) | n/a | -20 | -23 | ||||
| Interior | n/a | -9 | -7 | ||||||
| tissue | -5 | PC** | -9 | -5 | -9 | Yes | about 1 | < 10 | Villemure et al. 2007 [14] |
| tissue | -10 | Axial (long bone axis) | -2 | -9 | -4 | No | 3.4 | 70 | Amini et al. 2013 [45] |
| Transverse | +1 | +1 | +2 | ||||||
| cell | -15 | Minor diameter | -8 | -20 | -18 | No | 3.2 | 70 | Amini et al. 2010 [12] |
| Major diameter | -11 | -14 | -18 |
RZ: reserve zone. PZ: proliferative (columnar zone). HZ: hypertrophic zone. PC: principal compressive *logarithmic (present study) or **Lagrangian strain (Villemure et al.) strain. Surface: strains within certain depths of sample surface. Interior: strains at central region of the sample. Axial strain: along the bone long axis. Cell strains were reported as minor and major cell diameter changes. Minor diameter: cells in the PZ have minor diameters in line with the axial direction.