Fig 7. The KEGG pathway analysis of predicted targets differentially expressed miRNAs with P< 0.05.

Note: The enrichment p-value calculated by the calculating formula:

$$P=1-{\displaystyle \sum }_{i=0}^{m-1}\frac{\left(\frac{M}{i}\right)\left(\frac{N-M}{n-i}\right)}{\frac{N}{n}}$$

N was the number of all genes with KEGG annotation, n was the number of target gene candidates in N, M was the number of all genes annotated to a certain pathway, m was the number of target gene candidates in M.