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. 2015 Apr 17;10(4):e0122202. doi: 10.1371/journal.pone.0122202

Table 6. Differential expression levels of miRNAs between R and P libraries.

Index miR name miR seq R-NE P-NE log2 (R/P) fold (R/P) P-value
1 hsa-mir-7641-2-p5 ATCTCGGAAGCTAAGCAGGGTC 2334.57 657.07 1.83 3.55 0.00
2 oar-miR-22-3p_R+1 AAGCTGCCAGTTGAAGAACTGT 72245.41 23822.97 1.60 3.03 0.00
3 hsa-miR-34c-5p AGGCAGTGTAGTTAGCTGATTGC 2777.84 1090.26 1.35 2.55 0.00
4 hsa-miR-34a-5p TGGCAGTGTCTTAGCTGGTTGT 2522.03 830.34 1.60 3.04 0.00
5 hsa-miR-141-3p_R-1 TAACACTGTCTGGTAAAGATG 28337.35 5791.48 2.29 4.89 0.00
6 hsa-miR-449a TGGCAGTGTATTGTTAGCTGGT 1842.72 16.28 6.82 113.18 0.00
7 hsa-mir-7641-2-p3_1ss22TC GAAGCTAAGCAGGGTCGGGCCC 3564.20 929.19 1.94 3.84 0.00
8 bta-miR-31_R+2 AGGCAAGATGCTGGCATAGCTGT 3547.01 1305.99 1.44 2.72 0.00
9 hsa-miR-141-3p_R+1 TAACACTGTCTGGTAAAGATGGC 1673.33 252.36 2.73 6.63 0.00
10 cgr-miR-142-5p_L-2R+1 CATAAAGTAGAAAGCACTACT 5689.25 2523.59 1.17 2.25 0.00
11 bta-miR-182 TTTGGCAATGGTAGAACTCACACT 3518.63 241.89 3.86 14.55 0.00
12 cgr-miR-200c TAATACTGCCGGGTAATGATGGA 1555.52 316.32 2.30 4.92 0.00
13 ptr-miR-203_L-1R+1 TGAAATGTTTAGGACCACTAGT 1896.90 230.26 3.04 8.24 0.00
14 bta-miR-204 TTCCCTTTGTCATCCTATGCCT 2120.46 608.22 1.80 3.49 0.00
15 hsa-miR-204-5p TTCCCTTTGTCATCCTATGCCT 2116.17 607.06 1.80 3.49 0.00
16 bta-miR-339a_R+1 TCCCTGTCCTCCAGGAGCTCACT 1836.27 736.73 1.32 2.49 0.00
17 cfa-miR-375 TTTGTTCGTTCGGCTCGCGTGA 882.24 89.55 3.30 9.85 0.00
18 mmu-miR-6240_R-8_1ss1CA ACAAAGCATCGCGAAGGC 1583.04 381.45 2.05 4.15 0.00
19 PC-5p-2673_284 ACAGGATTGACAGATTGATAGCT 3335.48 1146.67 1.54 2.91 0.00
20 hsa-miR-200a-5p CATCTTACCGGACAGTGCTGGA 450.58 39.54 3.51 11.40 0.00
21 hsa-miR-187-3p_R+1 TCGTGTCTTGTGTTGCAGCCGGT 338.79 12.79 4.73 26.48 0.00
22 hsa-miR-17-5p CAAAGTGCTTACAGTGCAGGTAG 619.97 293.06 1.08 2.12 0.00
23 cgr-miR-142-3p_L+1R+1 TGTAGTGTTTCCTACTTTATGGA 423.49 185.49 1.19 2.28 0.00
24 hsa-mir-7641-2-p3_1ss1TC CGGTTAGTACTTGGATGGGA 311.28 81.41 1.93 3.82 0.00
25 bta-miR-6529 GAGAGATCAGAGGCGCAGAGT 281.18 69.78 2.01 4.03 0.00
26 hsa-miR-190a-5p_R+1 TGATATGTTTGATATATTAGGTT 335.35 133.74 1.33 2.51 0.00
27 bta-miR-183_L-1 ATGGCACTGGTAGAATTCACTG 153.92 3.49 5.46 44.12 0.00
28 PC-5p-5933_158 CTGTACCACCTTGTCGGG 164.24 13.96 3.56 11.77 0.00
29 PC-5p-6424_145 CAGCCTCTGGCATGTTGGA 196.05 37.21 2.40 5.27 0.00
30 bta-miR-132 TAACAGTCTACAGCCATGGTCG 271.72 117.46 1.21 2.31 0.00
31 bta-miR-15b TAGCAGCACATCATGGTTTACA 274.30 125.02 1.13 2.19 0.00
32 hsa-miR-4792_L+1R+1_1ss10GT CCGGTGAGCTCTCGCTGGCC 146.18 23.26 2.65 6.28 0.00
33 hsa-miR-31-3p_R+1 TGCTATGCCAACATATTGCCATC 188.31 73.27 1.36 2.57 0.00
34 hsa-miR-4454_L+1_1ss3GA CGAATCCGAGTCACGGCACCA 122.96 20.93 2.55 5.87 0.00
35 bta-miR-210_L-1R+1 CTGTGCGTGTGACAGCGGCTGAT 156.50 53.50 1.55 2.93 0.00
36 mmu-miR-22-5p_R-1 AGTTCTTCAGTGGCAAGCTTT 116.08 22.10 2.39 5.25 0.00
37 PC-5p-20799_45 GAGGGTTTGGGTTTGGTCGTGGGA 75.67 2.33 5.02 32.53 0.00
38 mmu-miR-3963_R+2_1ss1TC CGTATCCCACTTCTGACACCA 102.33 19.77 2.37 5.18 0.00
39 hsa-miR-132-5p ACCGTGGCTTTCGATTGTTACT 93.73 13.96 2.75 6.72 0.00
40 hsa-miR-184 TGGACGGAGAACTGATAAGGGT 72.23 2.33 4.96 31.05 0.00
41 rno-miR-147_R-1 GTGTGCGGAAATGCTTCTGCT 106.63 25.58 2.06 4.17 0.00
42 oar-miR-758-3p_R+2 TTTGTGACCTGGTCCACTAACT 106.63 29.07 1.87 3.67 0.00
43 cgr-miR-32-5p TATTGCACATTACTAAGTTGC 109.20 32.56 1.75 3.35 0.00
44 bta-miR-2478_L+2 TCGTATCCCACTTCTGACACCA 98.89 24.42 2.02 4.05 0.00
45 hsa-miR-24-1-5p_L+1_3ss17TA19TC20-A GTGCCTACTGAGCTGAAACACAGT 108.34 43.03 1.33 2.52 0.00
46 oan-miR-1386_L+4 TCGGCTCCTGGCTGGCTCGCCA 87.71 32.56 1.43 2.69 0.00
47 oan-miR-429-3p_R+2 TAATACTGTCTGGTAATGCCGTAA 49.87 3.49 3.84 14.30 0.00
48 hsa-miR-9-3p_L-1R+1 TAAAGCTAGATAACCGAAAGTA 63.63 14.54 2.13 4.38 0.00
49 ggo-miR-203b TTGAACTGTTAAGAACCACTGG 63.63 20.93 1.60 3.04 0.00
50 PC-5p-35677_26 CTCCGTCCCGGGACCCGGG 53.31 11.63 2.20 4.58 0.00
51 PC-3p-25064_36 TGACTTCCCCCTGTCCACTCAGT 36.11 1.16 4.96 31.05 0.00
52 PC-5p-10782_91 CTTGACTCTAGTCTGGCA 65.35 25.58 1.35 2.55 0.00
53 PC-5p-26648_38 TCCCGGGGCCGAGGGAGCC 45.57 9.30 2.29 4.90 0.00
54 PC-3p-16127_59 AAGGAAAATGTTCTTATTTT 45.57 12.79 1.83 3.56 0.00
55 hsa-miR-153-3p TTGCATAGTCACAAAAGTGATC 54.17 25.58 1.08 2.12 0.00
56 bta-miR-96 TTTGGCACTAGCACATTTTTGCT 31.82 4.65 2.77 6.84 0.00
57 hsa-miR-26b-3p CCTGTTCTCCATTACTTGGCTC 44.71 17.44 1.36 2.56 0.00
58 mmu-miR-3968_1ss14AT CGAATCCCACTCCTGACACCA 25.80 3.49 2.89 7.39 0.00
59 hsa-miR-34c-3p AATCACTAACCACACGGCCAGG 32.68 9.30 1.81 3.51 0.00
60 PC-3p-36269_24 CGCCCCACCCCGCTGCGGGC 24.08 2.33 3.37 10.35 0.00
61 hsa-miR-21-5p_R+2_1ss4CN TAGNTTATCAGACTGATGTTGACC 22.36 2.33 3.26 9.61 0.00
62 mmu-miR-503-5p TAGCAGCGGGAACAGTACTGCAG 26.66 5.81 2.20 4.58 0.00
63 bta-miR-2285f_L+1R-1 AAAAACCTGAATGAACTTTTTG 25.80 6.98 1.89 3.70 0.00
64 bta-miR-6123_R+1 TGCCAAGCCCACGTTCAAAGGC 28.38 9.30 1.61 3.05 0.00
65 ppy-miR-1260b_R+2_1ss9AG ATCCCACCGCTGCCACCATT 32.68 16.28 1.00 2.01 0.00
66 bta-miR-212 ACCTTGGCTCTAGACTGCTTACT 17.20 2.33 2.89 7.39 0.00
67 hsa-miR-212-5p ACCTTGGCTCTAGACTGCTTACT 17.20 2.33 2.89 7.39 0.00
68 hsa-miR-212-3p TAACAGTCTCCAGTCACGGCC 19.78 5.81 1.77 3.40 0.00
69 cgr-miR-32-3p CAATTTAGTGTGTGTGATATT 18.06 4.65 1.96 3.88 0.00
70 hsa-miR-340-3p_R+1 TCCGTCTCAGTTACTTTATAGCC 17.63 4.65 1.92 3.79 0.00
71 bta-miR-340 TCCGTCTCAGTTACTTTATAGCC 17.63 4.65 1.92 3.79 0.00
72 bta-miR-2427_L+1R-1 TAGGTCATTTCAAAGAGGGCT 13.76 2.33 2.56 5.92 0.00
73 hsa-miR-190a-3p_L+1 ACTATATATCAAACATATTCCT 15.48 3.49 2.15 4.44 0.00
74 oar-miR-154b-3p_L-1 ATCATACATGGTTGACCTTTTT 12.04 1.16 3.37 10.35 0.00
75 bta-miR-545-3p_L-1R+1 TCAACAAACATTTATTGTGTGC 21.50 10.47 1.04 2.05 0.00
76 hsa-miR-141-5p_1ss11TC CATCTTCCAGCACAGTGTTGGA 11.18 1.16 3.26 9.61 0.00
77 hsa-miR-491-3p CTTATGCAAGATTCCCTTCTAC 13.33 3.49 1.93 3.82 0.00
78 PC-3p-61660_13 CGCCTGTCTGAGCCTCGCT 17.20 8.14 1.08 2.11 0.00
79 PC-3p-99692_7 TCCGCCGGCCTTGCGGGCC 11.18 2.33 2.26 4.81 0.00
80 PC-5p-91245_7 CGCGCGCGGGGCCCGGGG 9.46 1.16 3.02 8.13 0.00
81 PC-5p-60249_14 ATTCCTATAATTCTAGCCA 10.32 2.33 2.15 4.44 0.00
82 PC-3p-215602_2 TGCAAAGAGGTTGGATCGAGT 7.74 1.16 2.73 6.65 0.00
83 PC-3p-82208_8 AAGGAGGTGCTGGTTGCTTT 7.74 1.16 2.73 6.65 0.00
84 bta-mir-2285o-3-p5_1ss12TC AAAAATTTGTTCGGGTTTTTCT 9.46 2.33 2.02 4.07 0.00
85 hsa-miR-139-3p TGGAGACGCGGCCCTGTTGGAGT 8.60 2.33 1.89 3.70 0.00
86 cgr-miR-139-3p TGGAGACGCGGCCCTGTTGGAGT 8.60 2.33 1.89 3.70 0.00
87 bta-miR-2284ab TAAAAGTTTGGTTGGGTTTTT 12.04 5.81 1.05 2.07 0.00
88 PC-5p-108241_6 ATACCGGGTGCTAGGCTT 6.88 1.16 2.56 5.92 0.00
89 mdo-miR-22-3p_R+1 AAGCTGCCAGTTGAAGAACTGCA 7.74 2.33 1.73 3.33 0.00
90 hsa-miR-185-3p_L+1R-1_1ss22TC CAGGGGCTGGCTTTCCTCTGGC 7.74 2.33 1.73 3.33 0.00
91 eca-miR-219-5p_R+2 TGATTGTCCAAACGCAATTCTCG 9.03 4.07 1.15 2.22 0.00
92 hsa-miR-26a-1-3p_1ss9TC CCTATTCTCGGTTACTTGCACG 7.74 3.49 1.15 2.22 0.00
93 hsa-miR-122-5p_R-1 TGGAGTGTGACAATGGTGTTT 7.74 3.49 1.15 2.22 0.00
94 PC-5p-139329_4 GGGTGCTGATAGTGAGGC 7.74 3.49 1.15 2.22 0.00
95 bta-miR-2284d_L-1R+1_1ss10GA AAAAGTTCATTAGGGTTTTTCT 6.02 0.58 3.37 10.35 0.00
96 bta-mir-2284z-4-p5_1ss1AG GAAAGTTTGTTTGGGTTTTTCT 9.46 4.65 1.02 2.03 0.00
97 bta-mir-2887-2-p5_1ss7AC CGGGACCCGGGGCGCGGC 6.02 2.33 1.37 2.59 0.00
98 bta-miR-677_R+1 CTCACTGATGAGCAGCTTCTGACT 6.02 2.33 1.37 2.59 0.00
99 hsa-miR-153-5p_L+1_2ss15G-16TC GTCATTTTTGTGATCTGCAGCT 5.16 1.16 2.15 4.44 0.01
100 bta-miR-2285r_R-2 AGAAACCTGGATGAACTTTTT 5.16 1.16 2.15 4.44 0.01
101 hsa-miR-628-3p_L+1 TTCTAGTAAGAGTGGCAGTCGA 4.73 0.58 3.02 8.13 0.01
102 hsa-miR-138-5p AGCTGGTGTTGTGAATCAGGCCG 4.73 2.33 1.02 2.03 0.01
103 hsa-miR-4791_1ss17AT TGGATATGATGACTGATA 4.73 2.33 1.02 2.03 0.01
104 hsa-miR-377-3p ATCACACAAAGGCAACTTTTGT 4.30 1.16 1.89 3.70 0.02
105 ssc-miR-671-5p AGGAAGCCCTGGAGGGGCTGGAGG 4.30 1.16 1.89 3.70 0.02
106 bta-miR-671_R+1 AGGAAGCCCTGGAGGGGCTGGAGG 4.30 1.16 1.89 3.70 0.02
107 PC-5p-203577_2 AAGAAGTTCATTCGGGTTTTTC 4.30 1.16 1.89 3.70 0.02
108 PC-5p-94605_6 GCTGGCCTGGAGCCGGGCG 4.30 1.16 1.89 3.70 0.02
109 PC-3p-247920_2 CTGGATATCTGAGACTCAGTTT 4.30 1.16 1.89 3.70 0.02
110 PC-5p-125235_4 GCCAAAAAGTTTGTTTGGGCTTT 4.30 1.16 1.89 3.70 0.02
111 oar-miR-10a_R+1_1ss12TA TACCCTGTAGAACCGAATTTGT 153958.53 657181.33 0.23 -2.09 0.00
112 oar-miR-10b_L+1R-1 TACCCTGTAGAACCGAATTTGT 160641.52 718168.02 0.22 -2.16 0.00
113 oar-miR-26b_R+1 TTCAAGTAATTCAGGATAGGTT 59229.84 124009.11 0.48 -1.07 0.00
114 oar-miR-26a TTCAAGTAATCCAGGATAGGCT 142846.73 330581.63 0.43 -1.21 0.00
115 cgr-miR-101b-3p_1ss22GT TACAGTACTGTGATAACTGAAT 8689.09 43584.93 0.20 -2.33 0.00
116 aja-miR-143_1ss22GT TGAGATGAAGCACTGTAGCTCT 289634.30 1866274.04 0.16 -2.69 0.00
117 oar-miR-133_L+1 TTTGGTCCCCTTCAACCAGCTGT 144.89 3558.04 0.04 -4.62 0.00
118 cfa-miR-145 GTCCAGTTTTCCCAGGAATCCCT 2123.04 11338.73 0.19 -2.42 0.00
119 bta-miR-490_R+1 CAACCTGGAGGACTCCATGCTGT 103.19 1465.31 0.07 -3.83 0.00
120 bta-miR-335_R-1 TCAAGAGCAATAACGAAAAATG 143.60 1430.42 0.10 -3.32 0.00
121 cfa-miR-196b TAGGTAGTTTCCTGTTGTTGGGA 2885.76 5979.87 0.48 -1.05 0.00
122 mdo-miR-181b-5p AACATTCATTGCTGTCGGTGGGT 3169.52 7213.76 0.44 -1.19 0.00
123 oar-miR-181a AACATTCAACGCTGTCGGTGAGT 20920.02 55420.24 0.38 -1.41 0.00
124 hsa-miR-181c-5p_R+1 AACATTCAACCTGTCGGTGAGTT 4420.64 10611.89 0.42 -1.26 0.00
125 hsa-miR-192-5p CTGACCTATGAATTGACAGCC 2454.10 5510.04 0.45 -1.17 0.00
126 hsa-miR-28-3p_1ss11TA CACTAGATTGAGAGCTCCTGGA 972.52 3577.22 0.27 -1.88 0.00
127 oar-miR-133_L+1R-2 TTTGGTCCCCTTCAACCAGCT 0.43 64.54 0.01 -7.23 0.00
128 ptr-miR-92_R+2 TATTGCACTTGTCCCGGCCTGTAA 1121.86 2665.86 0.42 -1.25 0.00
129 hsa-miR-100-5p AACCCGTAGATCCGAACTTGTG 416.18 915.24 0.45 -1.14 0.00
130 hsa-miR-767-5p_R-3 TGCACCATGGTTGTCTGAGC 2.58 56.98 0.05 -4.47 0.00
131 hsa-miR-490-5p CCATGGATCTCCAGGTGGGT 10.32 93.04 0.11 -3.17 0.00
132 bta-miR-320a AAAAGCTGGGTTGAGAGGGCGA 2877.59 9040.17 0.32 -1.65 0.00
133 hsa-miR-299-3p_1ss10TC TATGTGGGACGGTAAACCGCTT 141.88 297.71 0.48 -1.07 0.00
134 hsa-miR-133a-5p AGCTGGTAAAATGGAACCAAAT 0.43 19.77 0.02 -5.52 0.00
135 hsa-miR-335-3p TTTTTCATTATTGCTCCTGACC 42.99 198.86 0.22 -2.21 0.00
136 hsa-miR-1_1ss1TC CGGAATGTAAAGAAGTATGTAT 0.43 20.93 0.02 -5.61 0.00
137 age-miR-19a_1ss23AT TGTGCAAATCTATGCAAAACTGT 90.29 190.72 0.47 -1.08 0.02
138 hsa-miR-574-5p_R-2 TGAGTGTGTGTGTGTGAGTGT 166.67 386.68 0.43 -1.21 0.02
139 hsa-miR-374a-3p_R-1_1ss9AG CTTATCAGGTTGTATTGTAAT 164.24 382.61 0.43 -1.22 0.02
140 hsa-miR-143-5p_1ss22TA GGTGCAGTGCTGCATCTCTGGA 238.19 576.82 0.41 -1.28 0.02
141 mdo-miR-599-5p_R-2_1ss9TG TTTGATAAGCTGACATGGGAC 0.86 20.93 0.04 -4.61 0.02
142 hsa-miR-499a-5p TTAAGACTTGCAGTGATGTTT 63.63 130.25 0.49 -1.03 0.03
143 bta-mir-2285m-3-p5_1ss1AG GAAAGGTTCATTTGGGTTTTT 53.74 108.15 0.50 -1.01 0.03
144 bta-miR-216a_R-2 TAATCTCAGCTGGCAACTGT 0 18.61 - - -
145 bta-miR-431_R-3 TGTCTTGCAGGCCGTCATGC 12.90 0 - - -

Note: R-NE represented the normalized expression level of miRNAs in the small RNA library generated from receptive endometrium of Xinong Saanen dairy goats. P-NE represented the normalized expression level of miRNAs in the small RNA library generated from pre-receptive endometrium of Xinong Saanen dairy goats. Fold (R/P) and log2 (R/P) indicated the fold change of the miRNAs between samples. P-Value manifested the significance of miRNAs differential expression between two samples.