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Antiproliferative effect of anticancer drugs in 2-D monolayer model and 3-D core-shell beads. Docetaxel: IC50 was 11 μM in 2-D monolayer, 27 μM in 3-D culture; Tamoxifen: IC50 was 9 μM in 2-D monolayer, 58 μM in 3-D culture. 90% confidence intervals on the nonlinear regression fit parameters including the IC50s were calculated during the fitting process.
