Table 2.
All patients |
Other BPLMs but no β-blockers |
β-Blockers plus other BPLMs |
β-Blockers only (β-blockers but no other BPLMs) |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CPRD |
DIN |
CPRD |
DIN |
CPRD |
DIN |
CPRD |
DIN |
|||||||||
N | Per cent | N | Per cent | N | Per cent | N | Per cent | N | Per cent | N | Per cent | N | Per cent | N | Per cent | |
All patients | 11 302 | 100 | 3462 | 100 | 7272 | 64.3 | 2056 | 59.4 | 2832 | 25.10 | 864 | 24.4 | 1198 | 10.6 | 542 | 15.7 |
Deaths | 5754 | 50.1 | 1441 | 41.6 | 3748 | 51.6 | 846 | 41.2 | 1459 | 51.5 | 350 | 40.5 | 547 | 45.7 | 245 | 45.2 |
Alive at 1-year follow-up | 8763 | 77.5 | 2576 | 74.4 | 5607 | 77.1 | 1541 | 75.0 | 2194 | 77.5 | 630 | 72.9 | 962 | 80.3 | 405 | 74.7 |
On non-selective β-blocker | 685 | 6.06 | 239 | 7.5 | NA | NA | NA | NA | 359 | 12.7 | 71 | 8.2 | 326 | 27.2 | 167 | 30.8 |
Cancer sites | ||||||||||||||||
Breast | 2943 | 26.0 | 984 | 28.4 | 1746 | 24.0 | 554 | 26.9 | 794 | 28.0 | 240 | 27.8 | 403 | 33.6 | 194 | 35.8 |
Colon | 1799 | 15.9 | 619 | 17.9 | 1104 | 15.2 | 354 | 17.2 | 476 | 16.8 | 162 | 18.7 | 219 | 18.3 | 103 | 18.9 |
Lung | 1326 | 11.7 | 436 | 12.6 | 913 | 12.6 | 277 | 13.5 | 307 | 10.9 | 105 | 12.1 | 106 | 8.8 | 54 | 9.9 |
Oesophagus | 434 | 3.8 | 159 | 4.6 | 257 | 3.5 | 95 | 4.6 | 116 | 4.1 | 44 | 5.1 | 61 | 5.1 | 20 | 3.7 |
Ovarian | 203 | 1.8 | 148 | 4.3 | 124 | 1.7 | 76 | 3.7 | 45 | 1.6 | 43 | 5.0 | 34 | 2.8 | 29 | 5.4 |
Pancreas | 376 | 3.3 | 140 | 4.0 | 222 | 3.1 | 83 | 4.0 | 111 | 4.0 | 34 | 3.9 | 43 | 3.6 | 23 | 4.2 |
Prostate | 3748 | 33.2 | 759 | 21.9 | 2604 | 35.8 | 500 | 24.3 | 856 | 30.2 | 182 | 21.0 | 288 | 24.0 | 77 | 14.1 |
Renal | 141 | 1.2 | 124 | 3.6 | 81 | 1.1 | 69 | 3.4 | 48 | 1.7 | 33 | 3.8 | 12 | 1.0 | 22 | 4.0 |
Stomach | 332 | 2.9c | 93 | 2.7 | 221 | 3.0 | 52 | 2.5 | 79 | 2.8 | 21 | 2.4 | 32 | 2.7 | 20 | 3.7 |
BPLMs, blood pressure lowering medicines; CPRD, Clinical Practice Research Datalink; DIN, Doctors’ Independent Network; NA, not applicable.