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Three potential outcomes of a rapamycin dose response trial for effects on lifespan. The solid blue line represents the published data from the Interventions Testing Program for the effect of encapsulated rapamycin on mean lifespan of UMHET3 mice when provided in the diet beginning at 9 months of age (average of effects in males and females combined). Dashed lines represent a few possible outcomes of a dose response trial for rapamycin at higher doses.
