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. 2014 Oct 28;71(1):1–14. doi: 10.1111/biom.12248

Table 3.

The definitions of all natural path-specific effects when there are two mediators that are not causally ordered. There are four versions (one level-0, two level-1, and one level-2) of each of the three effects (direct, indirect through Inline graphic, and indirect through Inline graphic; note that there is no effect through both Inline graphic and Inline graphic when the mediators are not causally ordered)

Path Level Effect Definition
0 Inline graphic Inline graphic
Direct 1 Inline graphic Inline graphic
(through Inline graphic) 1 Inline graphic Inline graphic
2 Inline graphic Inline graphic
0 Inline graphic Inline graphic
Indirect 1 Inline graphic Inline graphic
through Inline graphic 1 Inline graphic Inline graphic
2 Inline graphic Inline graphic
0 Inline graphic Inline graphic
Indirect 1 Inline graphic Inline graphic
through Inline graphic 1 Inline graphic Inline graphic
2 Inline graphic Inline graphic